Prospective Evaluation of Operating Characteristics of Prostate Cancer Detection Biomarkers
نویسندگان
چکیده
منابع مشابه
Biomarkers for evaluation of prostate cancer prognosis.
Prostate cancer, with a lifetime prevalence of one in six men, is the second cause of malignancy-related death and the most prevalent cancer in men in many countries. Nowadays, prostate cancer diagnosis is often based on the use of biomarkers, especially prostate-specific antigen (PSA) which can result in enhanced detection at earlier stage and decreasing in the number of metastatic patients. H...
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After decades of near indifference to prostate cancer, the population and physicians have geared up to detect this potentially fatal malignancy at a stage before it spreads. This is in marked contrast to the past when prostate cancer was found most commonly when it had traveled through the blood stream into the bones and was incurable. New technology produces new questions. These include not on...
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Prostate-specific antigen (PSA) is widely used as a biomarker in the detection of prostate cancer and for decision making regarding treatment options, response to therapy, and clinical follow-up. Despite its widespread use, it is well recognised that PSA has suboptimal performance as a screening tool due to poor specificity, resulting in high negative biopsy rates and potential 'over-diagnosis'...
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Prostate cancer (CaP) continues to be the second leading cause of cancer-specific death in men in Western countries. The marker currently used for CaP detection is an increase in serum prostate specific antigen (PSA). However, the PSA test may give false positive or negative information and does not allow the differentiation of benign prostate hyperplasia (BPH), non-aggressive CaP and aggressiv...
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ژورنال
عنوان ژورنال: Journal of Urology
سال: 2011
ISSN: 0022-5347,1527-3792
DOI: 10.1016/j.juro.2010.08.088